BDBM365355 6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]-5-[4-({[(2- fluoro-5- methylphenyl)amino]carbonyl} amino)phenyl]nicotinamide::US10633373, Example 60::US10669265, Example 60::US9868726, Example 60

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1

InChI Key InChIKey=YEDBBOGEZDFFBL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365355   

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM365355(US9868726, Example 60 | 6-amino-N-[dimethyl(oxido)...)
Affinity DataIC50: 6nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM365355(US9868726, Example 60 | 6-amino-N-[dimethyl(oxido)...)
Affinity DataIC50: 6nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM365355(US9868726, Example 60 | 6-amino-N-[dimethyl(oxido)...)
Affinity DataIC50: 6nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent