BDBM365299 US9868720, No. 407::[2-Cyclobutyl-6-(1-oxetan- 3-yl-piperidin-3-yl)- pyrimidin-4-yl]-(4-trifluoro- methyl-pyridin-2-yl)-amine

SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)C2CCC2)C2CCCN(C2)C2COC2)c1

InChI Key InChIKey=AVPAXNCNRZGHCB-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365299   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365299(US9868720, No. 407 | [2-Cyclobutyl-6-(1-oxetan- 3-...)Copy SMILESCopy InChI

Affinity DataKi:  26nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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