BDBM365292 US9868720, No. 388::{2-(2-Methyl-2H-pyrazol- 3-yl)-6-[1-(tetrahydro- pyran-4-ylmethyl)- pyrrolidin-3-yl]-pyrimidin- 4-yl]-(4-trifluoromethyl- pyridin-2-yl)-amine

SMILES Cn1nccc1-c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(CC2CCOCC2)C1

InChI Key InChIKey=KXZPWPPJOKEBOG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365292   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365292(US9868720, No. 388 | {2-(2-Methyl-2H-pyrazol- 3-yl...)Copy SMILESCopy InChI

Affinity DataKi:  8.75nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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