BDBM365266 1-{4-[2-(3,4-Difluoro- pyrrolidin-1-yl)-6-(4- trifluoromethyl-pyridin-2- ylamino)-pyrimidin-4-yl]- piperidin-1-yl}-ethanone::US9868720, No. 250

SMILES CC(=O)N1CCC(CC1)c1cc(Nc2cc(ccn2)C(F)(F)F)nc(n1)N1CC(F)C(F)C1

InChI Key InChIKey=UMDBHPTXBUISBU-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365266   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365266(US9868720, No. 250 | 1-{4-[2-(3,4-Difluoro- pyrrol...)Copy SMILESCopy InChI

Affinity DataKi:  26.7nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL