BDBM365259 US9868720, No. 201::[2-(3,3-Difluoro-pyrrolidin- 1-yl)-6-piperidin-4- yl-pyrimidin-4-yl]-(4- thiophen-2-yl-pyridin-2-yl)- amine

SMILES FC1(F)CCN(C1)c1nc(Nc2cc(ccn2)-c2cccs2)cc(n1)C1CCNCC1

InChI Key InChIKey=CIGRSJBXDNLAEO-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365259   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365259(US9868720, No. 201 | [2-(3,3-Difluoro-pyrrolidin- ...)Copy SMILESCopy InChI

Affinity DataKi:  3.20nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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