BDBM365256 Cyclopropyl-{3-[2-(3,3- difluoro-pyrrolidin-1-yl)- 6-(4-trifluoromethyl- pyridin-2-ylamino)- pyrimidin-4-yl}-pyrrolidin- 1-yl}-methanone::US9868720, No. 184

SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)N2CCC(F)(F)C2)C2CCN(C2)C(=O)C2CC2)c1

InChI Key InChIKey=YWJULKHPLOSZKG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365256   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365256(US9868720, No. 184 | Cyclopropyl-{3-[2-(3,3- diflu...)Copy SMILESCopy InChI

Affinity DataKi:  41.5nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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