BDBM365253 3-{4-[2-(2-Methyl-pyrrolidin- 1-yl)-6-(4-trifluoromethyl- pyridin-2-ylamino)- pyrimidin-4-3yl]- piperidin-1-yl}-3-oxo- propionitrile::US9868720, No. 177

SMILES CC1CCCN1c1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCN(CC1)C(=O)CC#N

InChI Key InChIKey=HZNDYNWPBAPWQG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365253   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365253(US9868720, No. 177 | 3-{4-[2-(2-Methyl-pyrrolidin-...)Copy SMILESCopy InChI

Affinity DataKi:  8.03nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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