BDBM365249 3-Oxo-3-{4-[2-pyrrolidin- 1-yl-6-(4-trifluoromethyl- pyridin-2-ylamino)- pyrimidin-4-yl]-piperidin- 1-yl}-propionitrile::US9868720, No. 161

SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)N2CCCC2)C2CCN(CC2)C(=O)CC#N)c1

InChI Key InChIKey=OYQLYPMMQQKKGH-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365249   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365249(US9868720, No. 161 | 3-Oxo-3-{4-[2-pyrrolidin- 1-y...)Copy SMILESCopy InChI

Affinity DataKi:  15.3nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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