BDBM365243 (4-Methoxy-pyridin-2-yl)- [2-(2-methyl-pyrrolidin- 1-yl)-6-piperidin-4-yl- pyrimidin-4-yl]-amine::US9868720, No. 125

SMILES COc1ccnc(Nc2cc(nc(n2)N2CCCC2C)C2CCNCC2)c1

InChI Key InChIKey=NXRTUJOQTDITQF-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365243   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365243(US9868720, No. 125 | (4-Methoxy-pyridin-2-yl)- [2-...)Copy SMILESCopy InChI

Affinity DataKi:  15.2nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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