BDBM365222 (4-Fluoro-phenyl)-{3-[2- methyl-6-(4-trifluoro- methyl-pyridin-2-ylamino)- pyrimidin-4-yl]-piperidin- 1-yl}-methanone::US9868720, No. 22

SMILES Cc1nc(Nc2cc(ccn2)C(F)(F)F)cc(n1)C1CCCN(C1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=BCICRVQGVBUXHM-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365222   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365222(US9868720, No. 22 | (4-Fluoro-phenyl)-{3-[2- methy...)Copy SMILESCopy InChI

Affinity DataKi:  43.6nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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