BDBM365218 1-(3-(2-(1-methyl-1H-pyrazol-4-yl)-6-(4-methylpyridin-2-ylamino)pyrimidin-4-yl)piperidin-1-yl)ethanone::US9868720, No. 7

SMILES COc1cc(C)ccc1C(=O)N1CCCC(C1)c1cc(Nc2cc(C)ccn2)nc(C)n1

InChI Key InChIKey=KJNCJIXDQOEWLO-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365218   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

US Patent

LigandBDBM365218(US9868720, No. 7 | 1-(3-(2-(1-methyl-1H-pyrazol-4-...)Copy SMILESCopy InChI

Affinity DataKi:  20.7nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/10/2019
Entry Details
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