BDBM3649 3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}(methyl)amino)propane-1,2-diol::4-[(3-Bromophenyl)amino]-7-[N-(2,3-dihydroxypropyl)-N-methylamino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3g

SMILES CN(CC(O)CO)c1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key InChIKey=VHMBNNHFFIJPIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3649   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3649(4-[(3-Bromophenyl)amino]-7-[N-(2,3-dihydroxypropyl...)
Affinity DataIC50: 3.20nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed