BDBM3648 3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propane-1,2-diol::4-[(3-Bromophenyl)amino]-7-[(2,3-dihydroxypropyl)-amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 3f

SMILES OCC(O)CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key InChIKey=JLXPNVOGDZTOJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3648   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3648(3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin...)
Affinity DataIC50: 0.920nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed