BDBM364511 3-({[3-(1-methyl-1H-pyrazol-3-yl)- 4- (trifluoromethyl)phenyl]carbonyl} amino)-2-phenyl-2H-pyrazolo[4,3- b]pyridine-6-carboxamide::US9862707, Example 86

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1n(nc2cc(cnc12)C(N)=O)-c1ccccc1

InChI Key InChIKey=VXAVCZZIGYUMSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364511   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364511(US9862707, Example 86 | 3-({[3-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 2.80nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent