BDBM364395 US10913711, Compound 2z::US11555013, Compound 2z::US9862679, Compound 2z

SMILES Brc1ccc(cc1)C(SCC(=O)NCCCCc1ccccc1)c1ccc(Br)cc1

InChI Key InChIKey=PYFFLFRZZOWEGI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 364395   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi:  405nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi:  414nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi:  414nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi:  414nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi: >1.00E+5nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi: >1.00E+5nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM364395(US9862679, Compound 2z | US10913711, Compound 2z |...)
Affinity DataKi: >1.00E+5nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent