BDBM3642 2-[({4-[(3-bromophenyl)amino]-8H-pyrrolo[3,2-g]quinazolin-6-yl}methyl)(methyl)amino]acetic acid::5-[(3-bromophenyl)amino]-3-[[N-(carboxymethyl)-N-methylamino]methyl]pyrrolo[3,2-g]quinazoline hydrochloride::Pyrroloquinazoline deriv. 9

SMILES CN(CC(O)=O)Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12

InChI Key InChIKey=DBSQOKFNDAENBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3642   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3642(5-[(3-bromophenyl)amino]-3-[[N-(carboxymethyl)-N-m...)
Affinity DataIC50: 0.720nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3642(5-[(3-bromophenyl)amino]-3-[[N-(carboxymethyl)-N-m...)
Affinity DataIC50: 589nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed