BDBM364079 6-[3-fluoro-5-[[(1-methylazetidin-3-yl)amino]methyl]phenyl]pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 322

SMILES CN1CC(C1)NCc1cc(F)cc(c1)-c1ccc2ncnc(N)c2n1

InChI Key InChIKey=WVJZVNVHQJTDPS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364079   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364079(6-[3-fluoro-5-[[(1-methylazetidin-3-yl)amino]methy...)Copy SMILESCopy InChI

Affinity DataIC50: 124nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL