BDBM364071 N-[[3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-5-fluoro-phenyl]methyl]-N',N'-dimethyl-ethane-1,2-diamine::US9855269, Compound 314

SMILES CN(C)CCNCc1cc(F)cc(c1)-c1ccc2ncnc(N)c2n1

InChI Key InChIKey=PLPWLUBYLJLRHA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364071   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364071(N-[[3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-5-fluor...)Copy SMILESCopy InChI

Affinity DataIC50: 95.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
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