BDBM364056 6-[3-[(cyclobutylamino)methyl]-5-fluoro-phenyl]pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 299

SMILES Nc1ncnc2ccc(nc12)-c1cc(F)cc(CNC2CCC2)c1

InChI Key InChIKey=HQTWDDNBXZWJIP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364056   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364056(6-[3-[(cyclobutylamino)methyl]-5-fluoro-phenyl]pyr...)Copy SMILESCopy InChI

Affinity DataIC50: 140nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL