BDBM364028 6-[3-fluoro-5-(2-pyrrolidin-1-ylethylamino)phenyl]pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 271

SMILES Nc1ncnc2ccc(nc12)-c1cc(F)cc(NCCN2CCCC2)c1

InChI Key InChIKey=HFIRKJVPPWUORL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364028   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364028(US9855269, Compound 271 | 6-[3-fluoro-5-(2-pyrroli...)Copy SMILESCopy InChI

Affinity DataIC50: 88.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
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