BDBM363929 6-[3-(1,4-dimethylpyrazol-3-yl)-1-piperidyl]pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 172::US9855269, Compound 174

SMILES Cc1cn(C)nc1C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=LZVUDLPAGJKOHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363929   

LigandPNGBDBM363929(US9855269, Compound 172 | 6-[3-(1,4-dimethylpyrazo...)
Affinity DataIC50: 5.00E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM363929(US9855269, Compound 172 | 6-[3-(1,4-dimethylpyrazo...)
Affinity DataIC50: 32.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent