BDBM363812 7-Methoxy-1-oxo-2-(2-quinolin-2-yl-ethyl)-1,2-dihydro-isoquinoline-4-carboxylic acid butylamide::US9856220, Example 182

SMILES CCCCNC(=O)c1cn(CCc2ccc3ccccc3n2)c(=O)c2cc(OC)ccc12

InChI Key InChIKey=XHKHAFDLZYSJBG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363812   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
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US Patent

LigandBDBM363812(US9856220, Example 182 | 7-Methoxy-1-oxo-2-(2-quin...)Copy SMILESCopy InChI

Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
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