BDBM363782 2-Ethyl-7-methoxy-1-oxo-6-(2-quinolin-2-yl-ethoxy)-1,2-dihydro-isoquinoline-4-carboxylic acid butylamide::US9856220, Example 136

SMILES CCCCNC(=O)c1cn(CC)c(=O)c2cc(OC)c(OCCc3ccc4ccccc4n3)cc12

InChI Key InChIKey=AVBMZWJFBNIDIW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363782   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie Deutschland

US Patent

LigandBDBM363782(US9856220, Example 136 | 2-Ethyl-7-methoxy-1-oxo-6...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
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