BDBM363752 US9855229, Compound 6

SMILES OC(=O)c1ccc(N2C=C(C3C=CC=CC23)C(=O)c2c(Cl)cccc2Cl)c(F)c1

InChI Key InChIKey=QMIAFCWXOBFKAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363752   

TargetNuclear receptor ROR-gamma(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM363752(US9855229, Compound 6)
Affinity DataIC50: 2.18nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent