BDBM363493 Typical Example for Hydroamination::US9850245, Example 51

SMILES CC1=C(COC1=O)N1CCOC2(CCN(CCc3ccc(nn3)-n3cnnn3)CC2)C1=O

InChI Key InChIKey=PSOXQSRVRJHIJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363493   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM363493(US9850245, Example 51 | Typical Example for Hydroa...)
Affinity DataIC50: 7.30nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2019
Entry Details
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