BDBM36337 CID24762167::{4-[2-trans-(4-Amino-cyclohexylamino)-9-(3-benzyloxy-phenyl)-9H-purin-6-ylamino]-phenyl}-piperidin-1-yl-methanone, 5

SMILES NC1CCC(CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(OCc4ccccc4)c3)c2n1

InChI Key InChIKey=AWCNCBAUXOAKPA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36337   

TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandPNGBDBM36337(CID24762167 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Affinity DataIC50: 4.04E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
The Scripps Research Institute

LigandPNGBDBM36337(CID24762167 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Affinity DataEC50:  312nMpH: 7.5 T: 2°CAssay Description:This parasite proliferation assay, a modification of published DNA intercalating fluorescent dye-based assay, was adapted to 384-well plate format an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2011
Entry Details Article
PubMed