BDBM363351 (S)-4-((2-((3-cyano-4-fluorobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)amino)-3-hydroxybutanoic acid::US9850225, Example 1270

SMILES Cc1cc(CNC[C@@H](O)CC(O)=O)c(OCc2ccc(F)c(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1

InChI Key InChIKey=BMVKWRCPNMQQOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363351   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363351((S)-4-((2-((3-cyano-4-fluorobenzyl)oxy)-4-((3-(2,3...)
Affinity DataIC50: 5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent