BDBM36335 US10639284, Compound 1.001::US11426364, Compound 1.001

SMILES OC[C@H](NCc1cc(Cl)c(OC2CCc3c2cccc3-c2ccccc2)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key InChIKey=XFMADIVPJSLSMQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36335   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM36335(US10639284, Compound 1.001 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4 ° C. The wells were then blocked with PBS containing 2% BSA i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM36335(US10639284, Compound 1.001 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM36335(US10639284, Compound 1.001 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM36335(US10639284, Compound 1.001 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PD-1/PDL1 protein-protein interaction (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM36335(US10639284, Compound 1.001 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed