BDBM36325 Cathepsin Inhibitor III

SMILES COc1ccc(cc1)C(=O)ONC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=MWMGBOYXKWUFNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36325   

TargetCathepsin B(Rat)
Stanford University

LigandPNGBDBM36325(Cathepsin Inhibitor III)
Affinity DataIC50: 1.20E+3nMpH: 5.5 T: 2°CAssay Description:Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2011
Entry Details Article
PubMed
TargetCathepsin Z(Rat)
Stanford University

LigandPNGBDBM36325(Cathepsin Inhibitor III)
Affinity DataIC50: 1.50E+3nMpH: 5.5 T: 2°CAssay Description:Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2011
Entry Details Article
PubMed
TargetPro-cathepsin H(Rat)
Stanford University

LigandPNGBDBM36325(Cathepsin Inhibitor III)
Affinity DataIC50: 6.60E+3nMpH: 5.5 T: 2°CAssay Description:Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2011
Entry Details Article
PubMed