BDBM363164 Preparation of (R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-2-(4-fluoro-2-(methylsulfonyl)phenyl)-2-methoxyethanesulfonamide and (S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-2-(4-fluoro-2-(methylsulfonyl)phenyl)-2-methoxyethanesulfonamide::US9845310, Example 273.0

SMILES CO[C@H](CS(=O)(=O)N(CC[Si](C)(C)C)c1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ccc(F)cc1S(C)(=O)=O

InChI Key InChIKey=QKAIFGQZIHPXGL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363164   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM363164(Preparation of (R)-N-(4-(2,6-dimethoxyphenyl)-5-(6...)
Affinity DataEC50:  0.140nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2019
Entry Details
US Patent