BDBM3630 5-[(3-Bromophenyl)amino]-1-methylpyrrolo[3,2-g]-quinazoline::N-(3-bromophenyl)-8-methyl-8H-pyrrolo[3,2-g]quinazolin-4-amine::Pyrroloquinazoline deriv. 3b

SMILES Cn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc12

InChI Key InChIKey=QHAWLYRLLOXJAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3630   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3630(N-(3-bromophenyl)-8-methyl-8H-pyrrolo[3,2-g]quinaz...)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3630(N-(3-bromophenyl)-8-methyl-8H-pyrrolo[3,2-g]quinaz...)
Affinity DataIC50: 21.9nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed