BDBM362983 3-((1-(2-(4-(2-(1H-Pyrazol-1-yl)ethyl)piperidin-1-yl)-2-oxoethyl)-6-chloro-7-fluoro-2-methyl-1H-indol-3-yl)thio)benzoic acid ::US9850203, Compound 1-61

SMILES Cc1c(Sc2cccc(c2)C(O)=O)c2ccc(Cl)c(F)c2n1CC(=O)N1CCC(CCn2cccn2)CC1

InChI Key InChIKey=DCHYGUDCIWRZGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362983   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM362983(US9850203, Compound 1-61 | 3-((1-(2-(4-(2-(1H-Pyra...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
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