BDBM362980 3-((6-Chloro-1-(2-(5-methoxyindolin-1-yl)-2-oxoethyl)-7-fluoro-2-methyl-1H-indol-3-yl)thio)benzoic acid ::US9850203, Compound 1-58

SMILES COc1ccc2N(CCc2c1)C(=O)Cn1c(C)c(Sc2cccc(c2)C(O)=O)c2ccc(Cl)c(F)c12

InChI Key InChIKey=SXLGSOTYRSJTEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362980   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM362980(US9850203, Compound 1-58 | 3-((6-Chloro-1-(2-(5-me...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent