BDBM362966 3-((6-Chloro-7-fluoro-2-methyl-1-(2-(1′-methylspiro[indoline-3,4′-piperidin]-1-yl)-2-oxoethyl)-1H-indol-3-yl)thio)benzoic acid ::US9850203, Compound 1-38

SMILES CN1CCC2(CN(C(=O)Cn3c(C)c(Sc4cccc(c4)C(O)=O)c4ccc(Cl)c(F)c34)c3ccccc23)CC1

InChI Key InChIKey=LRWPMYQIHIGHHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362966   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM362966(US9850203, Compound 1-38 | 3-((6-Chloro-7-fluoro-2...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent