BDBM362939 3-((6-Chloro-7-fluoro-2-methyl-1-(2-((1-methyl-1H-pyrazol-4-yl)amino)-2-oxoethyl)-1H-indol-3-yl)thio)benzoic acid ::US9850203, Compound 1-6

SMILES CCOC(=O)c1cccc(Sc2c(C)n(CC(=O)Nc3cnn(C)c3)c3c(F)c(Cl)ccc23)c1

InChI Key InChIKey=FRNIUNKRQMHLCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362939   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM362939(US9850203, Compound 1-6 | 3-((6-Chloro-7-fluoro-2-...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent