BDBM362916 N-(4-(ethylsulfonyl)benzyl)-1-isopropyl-3-oxo-2-(4-(trifluoromethyl)benzyl)isoindoline-5-carboxamide Isomers::US9845308, Example 26a::US9845308, Example 26b

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3C(C(C)C)N(Cc4ccc(cc4)C(F)(F)F)C(=O)c3c2)cc1

InChI Key InChIKey=VFKHFGWTOYRRNZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362916   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362916(US9845308, Example 26a | US9845308, Example 26b | ...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362916(US9845308, Example 26a | US9845308, Example 26b | ...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent