BDBM362748 1-[6-[(2S)-Morpholin-2-yl]-3-pyridyl]-3-[3-(trifluoromethyl)phenyl]urea::US9840501, Example 42

SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(nc2)[C@@H]2CNCCO2)c1

InChI Key InChIKey=LGWAASGXZMUBAS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362748   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362748(US9840501, Example 42 | 1-[6-[(2S)-Morpholin-2-yl]...)
Affinity DataKi:  3nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM362748(US9840501, Example 42 | 1-[6-[(2S)-Morpholin-2-yl]...)
Affinity DataKi:  3.80nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
US Patent