BDBM362403 -(4-(3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)-2- fluorophenyl)acrylamide::US9834551, Example 62

SMILES Fc1cc(ccc1NC(=O)C=C)-c1cnc2[nH]cc(Cl)c2c1

InChI Key InChIKey=IWSUOOBXLHDPLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362403   

TargetTyrosine-protein kinase JAK3(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362403(US9834551, Example 62 | -(4-(3-chloro-1H-pyrrolo[2...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362403(US9834551, Example 62 | -(4-(3-chloro-1H-pyrrolo[2...)
Affinity DataIC50: 1.00E+3nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent