BDBM362383 N-(3-(3-(3,5-difluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-4-fluorophenyl)acrylamide ::US9834551, Example 40

SMILES COc1c(F)cc(F)cc1-c1c[nH]c2ncc(cc12)-c1cc(NC(=O)C=C)ccc1F

InChI Key InChIKey=ROAFFSOCHFCMLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362383   

TargetTyrosine-protein kinase JAK3(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362383(US9834551, Example 40 | N-(3-(3-(3,5-difluoro-2-me...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM362383(US9834551, Example 40 | N-(3-(3-(3,5-difluoro-2-me...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent