BDBM362364 4-(7-amino-3-{(2R)-4- [(3-methyloxetan-3- yl)carbonyl]morpholin- 2-yl}-1H-pyrazolo[3,4-c] pyridin-1-yl)-N-(4- methoxypyridin-2-yl)benzamide::US9834554, Example 8

SMILES COc1ccnc(NC(=O)c2ccc(cc2)-n2nc([C@H]3CN(CCO3)C(=O)C3(C)COC3)c3ccnc(N)c23)c1

InChI Key InChIKey=YWPUOGRCVDFYIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362364   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362364(US9834554, Example 8 | 4-(7-amino-3-{(2R)-4- [(3-m...)
Affinity DataIC50: 42.1nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
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