BDBM362363 4-{7-amino-3-[(2R)-4- (methoxyacetyl)morpholin-2-yl]-1H- pyrazolo[3,4-c]pyridin- 1-yl}-N-(4- methoxypyridin-2- yl)benzamide::US9834554, Example 7

SMILES COCC(=O)N1CCO[C@H](C1)c1nn(-c2ccc(cc2)C(=O)Nc2cc(OC)ccn2)c2c(N)nccc12

InChI Key InChIKey=WEUGVFUQYIWNJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362363   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362363(US9834554, Example 7 | 4-{7-amino-3-[(2R)-4- (meth...)
Affinity DataIC50: 25.2nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
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