BDBM362175 US10272077, Example 26::US9833448, Example 26

SMILES C[C@@H]1[C@@H](C[C@H](NC(=O)c2cnc3C[C@]4(Cc3c2)C(=O)Nc2ncccc42)C(=O)N1CC1(CC1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=GQEUXVCWAIGMFG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362175   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362175(US9833448, Example 26 | US10272077, Example 26)
Affinity DataKi:  0.0930nMAssay Description:Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-methylxanthine. Cells were then plated in a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362175(US9833448, Example 26 | US10272077, Example 26)
Affinity DataKi:  0.0930nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent