BDBM362123 (S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)amino)ethyl)-5-chloro-4-oxoquinazolin-3(4H)-yl)phenyl)-3-(2-(dimethylamino)ethyl)urea, trifluoroacetic acid salt::US10221197, Compound 116

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(NC(=O)NCCO)c1

InChI Key InChIKey=VFAPNHZRQIKKCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362123   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM362123((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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LigandPNGBDBM362123((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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LigandPNGBDBM362123((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent