BDBM362016 US10221197, Compound 10

SMILES NC(=O)c1cccc(c1)-n1c(nc2cccc(Cl)c2c1=O)[C@@H](Nc1nc(N)nc(N)c1Cl)C1CC1

InChI Key InChIKey=MAUPGTBUIGDPBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362016   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM362016(US10221197, Compound 10)
Affinity DataIC50: 7.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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LigandPNGBDBM362016(US10221197, Compound 10)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

LigandPNGBDBM362016(US10221197, Compound 10)
Affinity DataIC50: 2.70E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent