BDBM361979 4-[(2S)-2-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]amino}butanoyl]- 6,6-dimethylpiperazin-2-one::US10221178, Compound 4-7

SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CC(=O)NC(C)(C)C1

InChI Key InChIKey=RUVSGCRVUIAKSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361979   

LigandPNGBDBM361979(4-[(2S)-2-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H...)
Affinity DataIC50: 19nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent