BDBM361977 (S or R)-4-[(2S)-2-{[9-ethyl-8- (2-methylpyrimidin-5-yl)-9H- purin-6-yl]amino}butanoyl]- 1,6-dimethylpiperazin-2-one::US10221178, Compound 4-5::US10221178, Compound 4-6

SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CC(C)N(C)C(=O)C1

InChI Key InChIKey=PYDWWLYRUCYUCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 361977   

LigandPNGBDBM361977((S or R)-4-[(2S)-2-{[9-ethyl-8- (2-methylpyrimidin...)
Affinity DataIC50: 6.10nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM361977((S or R)-4-[(2S)-2-{[9-ethyl-8- (2-methylpyrimidin...)
Affinity DataIC50: 26nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent