BDBM361976 N-[(1S)-1-{[cis-4,4-difluoro- 3,5-dimethylpiperidin-1- yl]carbonyl}propyl]-9-ethyl-8- (2-methylpyrimidin-5-yl)-9H- purin-6-amine::US10221178, Compound 4-4
SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1C[C@H](C)C(F)(F)[C@H](C)C1
InChI Key InChIKey=UZUOCAARXNCASE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 361976
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 4.80nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
