BDBM361948 N-[(1S)-1-{[(cis)-2,6- dimethylmorpholin-4- yl]carbonyl}-2,2- dimethylpropyl]-9-ethyl-8-(2- methylpyrimidin-5-yl)-9H-purin- 6-amine::US10221178, Compound 2-42

SMILES CCn1c(nc2c(N[C@H](C(=O)N3C[C@H](C)O[C@H](C)C3)C(C)(C)C)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=YQXOKHQSIYQKQZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361948   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM361948(N-[(1S)-1-{[(cis)-2,6- dimethylmorpholin-4- yl]car...)Copy SMILESCopy InChI

Affinity DataIC50: 5.30nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/27/2019
Entry Details
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