BDBM361936 N-{(1S)-1-[((S and R)-3- cyclopropylmorpholin-4- yl)carbonyl]propyl}-9-ethyl-8-(2- methylpyrimidin-5-yl)-9H-purin- 6-amine::US10221178, Compound 2-30

SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CCOCC1C1CC1

InChI Key InChIKey=CKHMUOYYPGWORF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361936   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM361936(N-{(1S)-1-[((S and R)-3- cyclopropylmorpholin-4- y...)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/27/2019
Entry Details
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