BDBM361931 9-ethyl-8-(2-methylpyrimidin-5- yl)-N-[(1S)-1-(1,4-oxazepan-4- ylcarbonyl)propyl]-9H-purin-6- amine::US10221178, Compound 2-25

SMILES CC[C@H](Nc1ncnc2n(CC)c(nc12)-c1cnc(C)nc1)C(=O)N1CCCOCC1

InChI Key InChIKey=SHPBWNJEGSACPM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361931   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM361931(9-ethyl-8-(2-methylpyrimidin-5- yl)-N-[(1S)-1-(1,4...)Copy SMILESCopy InChI

Affinity DataIC50: 21nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/27/2019
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL